In Wilson disease, copper is not eliminated properly and instead accumulates, possibly to a life-threatening level. Symptoms include swelling, fatigue, abdominal pain, and uncontrolled or poorly coordinated movements.
  • 1 in 30,000 incidence rate
  • Caused by mutation in ATP7B gene
  • Results in build-up of copper in patients; may be fatal
  • Symptoms: Hepatic and neuronal impairment. Also, Kayser–Fleischer rings (as illustrated above)
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DPM-1001 Chelated Copper in Liver and Brain and Resulted in Elimination of Copper in Feces of Wilson Disease Toxic Milk Mouse Model

DepYmed is Exploring the Potential of DPM-1001 in Wilson Disease Patients

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